Extrahippocampal Desynchronization in Nonlesional Temporal Lobe Epilepsy

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Extrahippocampal Desynchronization in Nonlesional Temporal Lobe Epilepsy

Although temporal lobe epilepsy (TLE) is traditionally associated with both hypersynchronous activity in the form of interictal epileptic discharges and hippocampal sclerosis, recent findings suggest that desynchronization also plays a central role in the dynamics of this pathology. The objective of this work is to show the imbalance existing between mesial activities in patients suffering from...

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We have analysed retrospectively the clinical features and electroencephalograms in 35 patients with complex partial seizures of temporal lobe origin who were seizure-free after epilepsy surgery. Two groups were differentiated for statistical analysis: 16 patients had hippocampal temporal lobe seizures (HTS) and 19 patients had extrahippocampal temporal lobe seizures (ETS) associated with a sma...

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Extrahippocampal temporal lobe atrophy in temporal lobe epilepsy and mesial temporal sclerosis.

Visual inspection and volumetric analysis of MRIs allow mesial temporal sclerosis (MTS) to be reliably identified in patients with temporal lobe epilepsy. The presence of unilateral MTS ipsilateral to the side of habitual seizure onset is an indicator for the prognosis of good outcome after temporal lobe resection. There is evidence to suggest that widespread temporal lobe pathology, leading to...

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Temporal Lobe Epilepsy: Renewed Emphasis on Extrahippocampal Areas

Epilepsy is a chronic condition characterized by spontaneously recurring seizures. Although often viewed and discussed as a single clinical entity, epilepsy is a symptom of several disorders that affect the brain. The variety of causes is quite extensive and includes tumors, congenital malformations, genetic alterations in receptors or channels, and acquired structural abnormalities such as tho...

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ژورنال

عنوان ژورنال: Epilepsy Research and Treatment

سال: 2012

ISSN: 2090-1348,2090-1356

DOI: 10.1155/2012/823683